LIMR Seminar: Invention that tests electrical signals within the heart

Gan-Xin Yan, MD, PhD, LIMR professor, will give a talk about his innovation, the arterially perfused ventricular wedge preparation (wedge prep for short) that can accurately record all electrical signals in the heart, even in its innermost layers.

The wedge prep is now used by other research entities, and several pharmaceutical firms have sent representatives to LIMR to learn the technique from Dr. Yan. The FDA now requires experimental drugs to be tested to ensure they don’t cause long QT syndrome. Dr. Yan is testing wedge prep as an option to be used in preclinical studies for drug-induced long QT syndrome.

His talk, “Blinded validation of the rabbit ventricular wedge assay with 34 compounds including 28 CiPA drugs,” will be in McLean Conference Room, Lankenau Medical Center, on Thursday, Feb. 20, at 2 pm. All clinicians and researchers are welcome.

For more on Dr. Yan and his research, visit https://bit.ly/2Hacy3N

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Clinical Trial of the Week: Device trial for patients diagnosed with aortic stenosis

By Donna Loyle, communications specialist, LIMR

Main Line Health is participating in a clinical trial that is studying the safety and effectiveness of the ACURATE neo2™ aortic valve system for transcatheter aortic valve replacement in symptomatic patients diagnosed with aortic stenosis. Eligible patients are those at intermediate or greater risk for standard surgical aortic valve replacement.

Study participants undergo implantation with either the ACURATE neo2™ or another commercially available device. Patients will be assessed at baseline, peri- and post-procedure, at discharge, 30 days, six months, one year, and then annually for up to five years.

The Main Line Health principal investigator for the ACURATE IDE trial is Eric Gnall, DO. For more, visit https://www.mainlinehealth.org/research/clinical-trials/acurate-ide

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2020 United Way campaign now off and running!

Main Line Health’s 2020 United Way campaign is now underway! We are incredibly thankful to those of you who have generously donated in the past. With your help, we hope to raise as much as we can for those in our communities who need and depend on our support.

Any donation—no matter how large or small—is helping to make our communities stronger. From financial counseling and early childhood education services, to support for senior citizens and community resources for the unemployed, your donation demonstrates that your care and compassion for the community expands far beyond the walls of our organization.

This year, we’ve set a goal of $150,000—and we are confident that we can meet (and even exceed) that goal with your help. Regardless of how much you are able to donate, every dollar goes directly to those in our communities who need and depend on our support.

To make a donation to this year’s campaign—which will run through February 21—visit the United Way page on WellSpring or donate directly through PeopleSoft. You can also fill out the attached pledge form, and Payroll will enter your donation into PeopleSoft directly. You can mail your paper pledge form to Lisa Craig, MLH Finance, 3803 West Chester Pike, Newtown Square, PA 19073.

Thank you for your invaluable support as we demonstrate the power of Main Line Health in changing the lives of those who are most in need in our communities near and far.

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Upgrades coming to available payment methods in cafeterias

In an effort to enhance the experience and best meet the needs of staff and visitors in our retail areas, the Food Services team will be upgrading the payment systems and meal ordering kiosks in our cafeterias. Credit card readers will be replaced with new readers that allow users insert their chip. For payroll deductions, new proximity readers will require you to tap your badge instead of swiping. If you find your badge does not work with the new proximity reader, please go to your campus’ Public Safety office. Below is a schedule of the upgrades.

February 26, 2020 – Lankenau and Paoli

  • Credit card machines and proximity readers replaced.
  • Meal ordering kiosk software upgraded.

March 4, 2020 – Bryn Mawr Hospital, Bryn Mawr Rehab Hospital, Riddle Hospital, Mirmont

  • Credit card machines and proximity readers replaced at BMH, BMRH and Riddle.
  • Proximity readers replaced at Mirmont.
  • Meal ordering kiosks at BMH and Riddle will not be available on this day. Please place your order verbally with cafeteria staff.

March 5, 2020 – Bryn Mawr Hospital and Riddle Hospital

  • Meal ordering kiosk software upgraded.

Thank you for your cooperation as we work to improve the beneficial enhancements to all of our retail areas across the system.

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HHS Health Sector Cybersecurity Coordination Center (HC3) Warns of Coronavirus Themed E-mail Phishing

The U.S. Department of Health and Human Services Health Sector Cybersecurity Coordination Center (HC3) is warning of a new Coronavirus-themed phishing campaign that is attempting to capitalize on concerns about the Coronavirus. According to HC3, the phishing emails contain links to malware that is frequently used to target healthcare organizations and their IT systems. At least one campaign has been identified as attempting to impersonate the Centers for Disease Control and target Americans and other English-speaking victims.

Please continue to be vigilant and report any suspicious emails to the Service Desk.

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Clinical Trial of the Week: Interventional treatment study with brain radiotherapy in patients with small cell lung cancer

By Donna Loyle, communications specialist, LIMR

Researchers seek to determine how well whole-brain radiation therapy works and compares it with or without hippocampal avoidance in patients diagnosed with small cell lung cancer (SCLC). Avoiding the hippocampus during whole-brain radiation could decrease the chance of side effects on memory and thinking.

Clinical trial NRG CC0033 is a randomized phase II/III study in which all participants receive prophylactic cranial irradiation (PCI), a technique used to combat the occurrence of metastasis to the brain in highly aggressive cancers that commonly metastasize to the brain, most notably SCLC.

Eligible participants are randomized to one of the following two treatment arms:

  • Arm 1 (comparator): hippocampal avoidance PCI alone (25 Gy in 10 fractions)
  • Arm 2 (experimental): PCI with hippocampal avoidance using intensity-modulated radiation therapy (25 Gy in 10 fractions)

After completion of study treatment, patients are followed every three months for one year, then every six months for three years, and then annually.

Albert DeNittis, MD, and Paul Gilman, MD, are the principal investigators for this study. For more, visit https://www.mainlinehealth.org/research/clinical-trials/nrg-cc003

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Diabetes Seminar at LIMR

All clinicians are researchers are welcome to the one-hour seminar “Fructosamine-3-Kinase (FN3K): Housekeeper Enzyme or Paradoxical Role in the Pathogenesis of Diabetes Complications?” Thursday, Feb. 13 from 2 to 3 pm in McLean Conference Room, Lankenau Medical Center.

The speaker will be Melvin Reichman, PhD, senior investigator at LIMR. Before joining LIMR, Dr. Reichman spent 20 years in senior-level positions at major biotechnology companies. At LIMR he founded and directs the Chemical Genomics Center.

For more on his research:

https://www.mainlinehealth.org/research/lankenau-institute-for-medical-research/researchers/our-faculty/melvin-reichman

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Main Line HealthCare physician network welcomes Delaware County Family Practice

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Update from Physician Wellness Committee

Walter Klein, MD Chair and Susan Gregory, MD Vice Chair

Thank you to all on the medical staff who took time to complete our physician burnout survey this past fall.  We would like to share with you some of the key takeaways from the survey.  Of the total respondents (n=504), 53% described themselves as burnt out or having symptoms of burnout and 76% feel a great deal of stress because of their job.  Two aspects that respondents most often described as “poor” were having sufficient time for documentation (22%) and control over their workload (17%).  Use of the EHR at home was described as excessive for 21% of respondents.

When physicians were asked to elaborate more on their stressors at work, the main themes that stood out were that physicians needed more staff, they have a lot of frustration with EPIC and EHR’s in general and they are wanting a better work/life balance.  The overall results are in keeping with those of national surveys on physician burnout.

Our committee has since met to discuss the survey results in greater detail and what our next steps should be.  This is a very complex issue to tackle and while many changes will have to come from the federal government particularly with regard to regulations and compliance, we can still do things on a local level.  Our committee came up with three next steps:

  • Reduce unintended burden of EPIC by launching a link on Wellspring where all healthcare providers can nominate anything in EPIC that they thought was poorly designed, unnecessary, or just plain stupid. These would be studied by the appropriate EPIC committees to see if the change is feasible or not.
  • Improve existing physician lounges so that they are a warm, welcoming and inviting place for physicians to go to for down time, relaxing, taking a break, lunch, coffee etc. These exist in all four hospitals but have been ignored and abandoned for many years.  Of note Bryn Mawr’s was recently renovated.
  • Enable physicians to have more of a voice in issues related to workload, work-flow, and staffing in their practices. This request would be made directly to the appropriate department chairs and/or division chiefs.

Thanks again to all of you who completed the survey.  As always, our committee welcomes comments or suggestions at any time.

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2020 United Way campaign now off and running!

Main Line Health’s 2020 United Way campaign is now underway! We are incredibly thankful to those of you who have generously donated in the past. With your help, we hope to raise as much as we can for those in our communities who need and depend on our support.

Any donation—no matter how large or small—is helping to make our communities stronger. From financial counseling and early childhood education services, to support for senior citizens and community resources for the unemployed, your donation demonstrates that your care and compassion for the community expands far beyond the walls of our organization.

This year, we’ve set a goal of $150,000—and we are confident that we can meet (and even exceed) that goal with your help. Regardless of how much you are able to donate, every dollar goes directly to those in our communities who need and depend on our support.

To make a donation to this year’s campaign—which will run through February 21—visit the United Way page on WellSpring or donate directly through PeopleSoft. You can also fill out the attached pledge form, and Payroll will enter your donation into PeopleSoft directly. You can mail your paper pledge form to Lisa Craig, MLH Finance, 3803 West Chester Pike, Newtown Square, PA 19073.

Thank you for your invaluable support as we demonstrate the power of Main Line Health in changing the lives of those who are most in need in our communities near and far.

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