By Donna Loyle, communications specialist, LIMR
“Regulation of oncogene and oxidative stress responses by the ER stress sensor IRE1α” will be the topic of the next seminar hosted by the Lankenau Institute for Medical Research. Speaker Adam Glick, PhD, professor of molecular toxicology and carcinogenesis, Department of Veterinary and Biomedical Sciences, Penn State, will visit Lankenau on Thursday, June 13, at 2 p.m. in McLean Conference Room, Annenberg.
Dr. Glick notes that many studies point to a role for activation of the unfolded protein response in later stages of cancer; however, much less is known about these pathways in early stages of cancer and tumor progression. To help answer those questions, he will discuss studies from his lab that implicate the IRE1α pathway in the cellular response of epidermal keratinocytes to oncogenic Ras and UVB irradiation.
All clinicians and scientists are welcome to attend this one-hour seminar.