Clinical Trial of the Week: Phase II treatment study for breast cancer

By Donna Loyle, communications manager, LIMR


In this randomized phase II clinical trial, researchers are studying how well docetaxel or paclitaxel work in reducing chemotherapy-induced peripheral neuropathy in a patient cohort comprised of African American women diagnosed with stages I-III breast cancer.


Eligible participants must have had no prior taxane therapy and no prior or concurrent platinum-based chemotherapy. Also, they must have no pre-existing neuropathy.


Participants are grouped into two study arms:

  • Arm 1 receives paclitaxel IV once weekly. Treatment repeats every 21 days for 4 cycles.
  • Arm 2 receives docetaxel IV once every 3 weeks. Treatment repeats every 21 days.


Patients may also receive other medications at the physician’s discretion.


Study #EAZ171 is approved for all four MLH acute care hospitals. For more, email or visit

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